Mutations of WD repeat domain 62 (WDR62) lead to autosomal recessive primary microcephaly (MCPH), and down-regulation of WDR62 expression causes the loss of neural progenitor cells (NPCs).However, how Outdoor Dining Set WDR62 is regulated and hence controls neurogenesis and brain size remains elusive.Here, we demonstrate that mitogen-activated prot
Aging is a complex, yet pervasive phenomenon in biology.As human cells steadily succumb to the deteriorating effects of aging, so too comes a host of age-related ailments such as neurodegenerative disorders, cardiovascular disease and cancer.Therefore, elucidation of the molecular networks that drive aging is of paramount importance to human health
The Patagonian steppe is a refuge for several indigenous peoples who live in relatively isolated communities, depending heavily on natural resources for their activities, health, and food security.The local ecological knowledge is a reservoir that generates full wellbeing and for which it must be the object of protection and local development.In th
How can we effectively regularize BERT? Although BERT proves its effectiveness in various NLP tasks, it often overfits when there are only a small number of training instances.A promising direction to regularize BERT is based on pruning its attention heads with a proxy score for head importance.However, these methods are usually suboptimal since th
El envejecimiento de la población mundial y la cuestión de la dependencia en la vejez son dos desafíos sociales importantes que conducen a la creación de nuevos empleos, trabajos y profesiones.El objetivo de este artículo es analizar el modo en que está siendo constituida la profesión de cuidador de personas mayores en el Brasil.Con base en